Article Figures & Data
Figures
- Figure 1.
In vitro growth suppression of human esophageal squamous cell carcinoma (TE-2, T.Tn) cells irradiated with carbon-ion beam with or without 24h CHAP31 exposure before irradiation. Curves are normalized to CHAP31 treatment alone. C-ion; Carbon-ion irradiation.
- Figure 2.
The changes of gene expression of Rad50, Mre11A, Nbs1 and p21WAF1 after CHAP31 administration by quantitative real-time reverse transcription-PCR (qRT-PCR) analysis. Values shown are means ±standard deviation of 3 independent experiments. Control: untreated cells.
- Figure 3.
The effect of carbon-ion 3 Gy irradiation and/or CHAP31 (5mg/kg i.v.) on in vivo tumor growth of esophageal squamous cell carcinoma (TE-2, T.Tn). Values represent the mean and standard deviation of 5 mice. Control: untreated.
- Figure 4.
The Mre11-Rad50-Nbs1 (MRN) complex plays a crucial role in DNA double-strand break repair.
