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Research ArticleExperimental Studies

Establishment and Characterization of a Human Gastrointestinal Stromal Tumour (GIST) Xenograft in Athymic Nude Mice

MONA-ELISABETH REVHEIM, THERESE SEIERSTAD, JEANNE-MARIE BERNER, ØYVIND SVERRE BRULAND, KATHRINE RØE, HEGE OMA OHNSTAD, BODIL BJERKEHAGEN and TORE BACH-GANSMO
Anticancer Research November 2009, 29 (11) 4331-4336;
MONA-ELISABETH REVHEIM
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  • For correspondence: mona.elisabeth.revheim{at}radiumhospitalet.no
THERESE SEIERSTAD
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JEANNE-MARIE BERNER
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ØYVIND SVERRE BRULAND
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KATHRINE RØE
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HEGE OMA OHNSTAD
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BODIL BJERKEHAGEN
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TORE BACH-GANSMO
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    Figure 1.

    HE stain and immunohistological staining of CD117 of the initial human GIST metastasis and the GIST xenograft established from this tumour.

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    Figure 2.

    Sequencing of KIT exon 17 mutation (c.2446G>C, p.Asp816His) in A) the human GIST xenograft, B) the primary human GIST tumour prior to imatinib treatment and C) the human GIST metastasis after imatinib treatment.

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Anticancer Research
Vol. 29, Issue 11
November 2009
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Establishment and Characterization of a Human Gastrointestinal Stromal Tumour (GIST) Xenograft in Athymic Nude Mice
MONA-ELISABETH REVHEIM, THERESE SEIERSTAD, JEANNE-MARIE BERNER, ØYVIND SVERRE BRULAND, KATHRINE RØE, HEGE OMA OHNSTAD, BODIL BJERKEHAGEN, TORE BACH-GANSMO
Anticancer Research Nov 2009, 29 (11) 4331-4336;

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Establishment and Characterization of a Human Gastrointestinal Stromal Tumour (GIST) Xenograft in Athymic Nude Mice
MONA-ELISABETH REVHEIM, THERESE SEIERSTAD, JEANNE-MARIE BERNER, ØYVIND SVERRE BRULAND, KATHRINE RØE, HEGE OMA OHNSTAD, BODIL BJERKEHAGEN, TORE BACH-GANSMO
Anticancer Research Nov 2009, 29 (11) 4331-4336;
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