Breast Cancer in the Post-Genomic Era.

Edited by A. Giordano, , N. Normanno. 2009, pp. 230, Eur 139.95, ISBN: 978-1-60327-944-4. Humana Press, c/o Springer Science + Business Media, New York, NY, USA.

Breast cancer is the most common tumor in women and the second leading cause of cancer deaths worldwide. Due to breakthroughs in gene profiling, the knowledge of the pathophysiology of the mammary gland has greatly increased over the last decade. In this volume, Antonio Giordano, Nicola Normanno, and a panel of international authorities in their field provide a comprehensive approach to the biology, diagnosis, prevention, and treatment of human breast carcinoma. The book provides a comprehensive approach to breast cancer, describing the use of gene profiling techniques to distinguish specific features of individual carcinomas, as well as emerging novel therapeutic approaches to treatment. Additional chapters cover the use of transgenic mice to model human breast cancer and the role of the EGF-CFC family in mammary gland development and neoplasia. This book succeeds in looking at breast cancer pathogenesis, diagnosis, and treatment under a more comprehensive light, and is a valuable resource for any radiation or surgical oncologist, cancer biologist or pathologist.