Figure 2.
Effect of six selected compounds on PGE2 production by LPS-activated RAW264.7 cells. RAW264.7 cells were incubated for 24 hours without (control), or with the indicated concentrations of tropolone (T-3), 2,4-dibromo-7-methoxytropone (T-21), diethyl 2-chloroazulene-1,3-dicarboxylate (A-9), 1,3-difluoroazulene (A-11), 3-morpholino-1,5-azulenequinone (AQ-8), or 3,7-dibromo-1,5-azulenequinone (AQ-13), and the extracellular concentration of PGE2 was then measured.