Primary Uterine Leiomyosarcoma and Primary Atypical Meningioma Diagnosed during Pregnancy

Abstract

Objective: Uterine leiomyosarcoma during pregnancy is an extremely rare event. The incidence of meningioma during pregnancy is comparable with that in nonpregnant women of the same age group. We report a case of both - a primary uterine leiomyosarcoma and additionally an atypical meningioma of the brain both diagnosed during pregnancy. Case Report: The patient was admitted with generalised seizures at 31 weeks of gestation. A tumoural mass was detected and initial conservative treatment was started. The patient delivered her infant via caesarean section, at 34 weeks of gestation. During caesarean section a pedunculated uterine fibroid was removed and total gross resection due to the brain tumour was also performed. Histopathological diagnosis of both tumours revealed an atypical meningioma of the brain and a uterine leiomyosarcoma. The patient underwent laparatomy and received six cycles of adjuvant chemotherapy. Conclusion: We are the first to report a case of a woman with two separate primary neoplasms both diagnosed during pregnancy. Treatment options seem to be reduced in pregnant women and mainly depend on the patient's condition as well as the gestational age at presentation.