Abstract
Background: Gossypol has recently been identified as a potential anticancer agent. In this study, a novel liposomal formulation is evaluated for delivery of gossypol. Materials and Methods: Gossypol was incorporated into liposomes. The liposomes were characterized for physical and chemical properties and for in vitro cytotoxicity. Results: Gossypol was stably encapsulated in these liposomes and exhibited cytotoxicity towards cancer cells. Conclusion: Liposomes can be used effectively as gossypol carriers.
- Received March 11, 2008.
- Revision received June 12, 2008.
- Accepted June 19, 2008.
- Copyright© 2008 International Institute of Anticaner Research (Dr. John G. Delinassios), All rights reserved
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