Abstract
Colorectal cancer (CRC) cells (HT29) were injected into the intraperitoneal (i.p.) cavity of immunosuppressed male Sprague Dawley rats. Immunosuppression was achieved via a daily i.p. injection of cyclosporine 35 mg/kg/day. Three groups of rats (n=6 per group) were injected with 20, 50 or 100 million HT29 cells. All animals developed tumours indicating that this animal model may prove useful for future research in human colorectal carcinomatosis.
- Received July 12, 2007.
- Revision received November 14, 2007.
- Accepted December 10, 2007.
- Copyright© 2008 International Institute of Anticaner Research (Dr. John G. Delinassios), All rights reserved
