Anticancer Research: 27 (1A)

January-February 2007; Volume 27,Issue 1A

Experimental Studies

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Establishment of Human Cancer Cell Clones with Different Characteristics: A Model for Screening Chemopreventive Agents
JEFFREY H. WARE, ZHAOZONG ZHOU, JUN GUAN, ANN R. KENNEDY and LEVY KOPELOVICH

Anticancer Research January 2007, 27 (1A) 1-16;
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Polymorphonuclear Leukocytes Increase the Adhesion of Circulating Tumor Cells to Microvascular Endothelium
MIRANDA TEN KATE, AREND G.J. AALBERS, WIM SLUITER, LEO J. HOFLAND, PIETER SONNEVELD, JOHANNES JEEKEL and CASPER H.J. VAN EIJCK

Anticancer Research January 2007, 27 (1A) 17-22;
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Tumour Suppressor Protein (p53), Apoptosis Inhibiting Protein (Bcl-2) and Proliferating Cell Nuclear Antigen (PCNA) Expressions in a Rat Pancreatic Tumour Model
KIMMO MÄKINEN, SAMI LOIMAS, TAPIO HAKALA and MATTI ESKELINEN

Anticancer Research January 2007, 27 (1A) 23-26;
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mRNA Stability and Overexpression of Fatty Acid Synthase in Human Breast Cancer Cell Lines
DIRK A HUNT, HILARY M. LANE, MATTHEW E. ZYGMONT, PETER A. DERVAN and RANDOLPH A. HENNIGAR

Anticancer Research January 2007, 27 (1A) 27-34;
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Measuring Cytotoxicity: A New Perspective on LC₅₀
MING ZHANG, DOLLY AGUILERA, CHANDRA DAS, HERNAN VASQUEZ, PETER ZAGE, VIDYA GOPALAKRISHNAN and JOHANNES WOLFF

Anticancer Research January 2007, 27 (1A) 35-38;
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Stathmin is Overexpressed in Malignant Mesothelioma
JAE Y. KIM, CHANSONETTE HARVARD, LIANG YOU, ZHIDONG XU, KRISTOPHER KUCHENBECKER, RICK BAEHNER and DAVID JABLONS

Anticancer Research January 2007, 27 (1A) 39-44;
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Three-dimensional Cellular Spheroid Formation Provides Human Prostate Tumor Cells with Tissue-like Features
AKIMITSU TAKAGI, MASATOSHI WATANABE, YASUHISA ISHII, JOJI MORITA, YOSHIFUMI HIROKAWA, TAKESHI MATSUZAKI and TAIZO SHIRAISHI

Anticancer Research January 2007, 27 (1A) 45-53;
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The Biological Relevance of FHL2 in Tumour Cells and its Role as a Putative Cancer Target
KAI KLEIBER, KLAUS STREBHARDT and BERND T. MARTIN

Anticancer Research January 2007, 27 (1A) 55-61;
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Correlation of DNA Mismatch Repair Protein hMSH2 Immunohistochemistry with p53 and Apoptosis in Cervical Carcinoma
FRANK KÖSTER, ANDREAS SCHRÖER, DOROTHEA FISCHER, THOMAS GREWELDINGER, KLAUS DIEDRICH and MICHAEL FRIEDRICH

Anticancer Research January 2007, 27 (1A) 63-68;
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Short Tandem Repeat Polymorphisms of Exon 4 in Kazal-type Gene ECRG2 in Pancreatic Carcinoma and Chronic Pancreatitis
JUSSUF T. KAIFI, GUEL CATALDEGIRMEN, ROBIN WACHOWIAK, PAULUS G. SCHURR, HELGE KLEINHANS, GEORGIA KOSTI, EMRE F. YEKEBAS, OLIVER MANN, ASAD KUTUP, VIACHESLAV KALININ, TIM STRATE and JAKOB R. IZBICKI

Anticancer Research January 2007, 27 (1A) 69-73;
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FTY720 Induced Bcl-associated and Fas-independent Apoptosis in Human Renal Cancer Cells In Vitro and Significantly Reduced In Vivo Tumor Growth in Mouse Xenograft
TAKANOBU UBAI, HARUHITO AZUMA, YATSUGU KOTAKE, TERUO INAMOTO, KIYOSHI TAKAHARA, YUKO ITO, SATOSHI KIYAMA, TAKESHI SAKAMOTO, SHIGEO HORIE, SATORU MUTO, SHIRO TAKAHARA, YOSHINORI OTSUKI and YOJI KATSUOKA

Anticancer Research January 2007, 27 (1A) 75-88;
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Transcriptional Regulatory Regions of the Survivin Gene Activate an Exogenous Suicide Gene in Human Tumors and Enhance the Sensitivity to a Prodrug
KIYOKO KAWAMURA, LING YU, MINORU TOMIZAWA, OSAMU SHIMOZATO, GUANGYU MA, QUANHAI LI, AYAKO SATO, YANLING YANG, TAKEO SUZUKI, NASHWA MOHAMED ABDEL-AZIZ and MASATOSHI TAGAWA

Anticancer Research January 2007, 27 (1A) 89-93;
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Significance of Matrix Metalloproteinase-2, -11 and Tissue Inhibitor of Metalloproteinase-1 Expression in Normal, Hyperplastic and Neoplastic Endometrium
AKANE OBOKATA, JUN WATANABE, YUKARI NISHIMURA, TSUTOMU ARAI, MIWA KAWAGUCHI and HIROYUKI KURAMOTO

Anticancer Research January 2007, 27 (1A) 95-105;
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Modulation of Multidrug Resistance Gene Expression in Human Breast Cancer Cells by (-)-Gossypol-enriched Cottonseed Oil
WEIPING YE, HSIANG-LIN CHANG, LI-SHU WANG, YI-WEN HUANG, SHERRY SHU, MICHAEL K. DOWD, PETER J. WAN, YASURO SUGIMOTO and YOUNG C. LIN

Anticancer Research January 2007, 27 (1A) 107-116;
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ROS Mediates Baicalin-induced Apoptosis in Human Promyelocytic Leukemia HL-60 Cells through the Expression of the Gadd153 and Mitochondrial-dependent Pathway
HSU-FUNG LU, SHU-CHING HSUEH, YUNG-TSUAN HO, MING-CHING KAO, JAI-SING YANG, TSAN-HUNG CHIU, SHAU-YEN HUAMG, CHING-CHUNG LIN and JING-GUNG CHUNG

Anticancer Research January 2007, 27 (1A) 117-125;
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Overexpression of Human X-box Binding Protein 1 (XBP-1) in Colorectal Adenomas and Adenocarcinomas
TAKASHI FUJIMOTO, KAZUHIKO YOSHIMATSU, KIYO WATANABE, HAJIME YOKOMIZO, TAISUKE OTANI, ATSUO MATSUMOTO, GAKUJI OSAWA, MASAMITSU ONDA and KENJI OGAWA

Anticancer Research January 2007, 27 (1A) 127-131;
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Tumor-specificity and Type of Cell Death Induced by Trihaloacetylazulenes in Human Tumor Cell Lines
TAKASHI SEKINE, JURI TAKAHASHI, MASAYUKI NISHISHIRO, ATSUHIRO ARAI, HIDETSUGU WAKABAYASHI, TERUO KURIHARA, MASAKI KOBAYASHI, KEN HASHIMOTO, HIROTAKA KIKUCHI, TADASHI KATAYAMA, YUMIKO KANDA, SHIRO KUNII, NOBORU MOTOHASHI and HIROSHI SAKAGAMI

Anticancer Research January 2007, 27 (1A) 133-143;
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Up-regulation of Matrix Metalloproteinase Family Gene Involvement in Ursolic Acid-induced Human Lung Non-small Carcinoma Cell Apoptosis
MIAO Y. LAI, HENRY WING C. LEUNG, WEN H. YANG, WEN H. CHEN and HONG Z. LEE

Anticancer Research January 2007, 27 (1A) 145-153;
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Comparative Biology of Human and Canine Osteosarcoma
F. MUELLER, B. FUCHS and B. KASER-HOTZ

Anticancer Research January 2007, 27 (1A) 155-164;
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Renal Cell Carcinoma-induced Immunosuppression: An Immunophenotypic Study of Lymphocyte Subpopulations and Circulating Dendritic Cells
CAMILLO PORTA, LUCIA BONOMI, BEATRICE LILLAZ, CHIARA PAGLINO, BIANCA ROVATI, ILARIA IMARISIO, PATRIZIA MORBINI, CHIARA VILLA, MARCO DANOVA, MARIO MENSI and BRUNO ROVERETO

Anticancer Research January 2007, 27 (1A) 165-173;
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Association Between Duodenal Contents Reflux and Squamous Cell Carcinoma - Establishment of an Esophageal Cancer Cell Line Derived from the Metastatic Tumor in a Rat Reflux Model
KUAN-HAO CHEN, KEN-ICHI MUKAISHO, ZHI-QIANG LING, AKIHIKO SHIMOMURA, HIROYUKI SUGIHARA and TAKANORI HATTORI

Anticancer Research January 2007, 27 (1A) 175-181;
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Evaluation of Insulin-like Growth Factor-1 in a Mouse Model of Long-term Abdominal Radiation Toxicity
CARSTEN NIEDER, LU CAI, WOLFGANG A. WEBER, SABINE SCHILL, NICOLAUS ANDRATSCHKE, MARKUS SCHWAIGER and MICHAEL MOLLS

Anticancer Research January 2007, 27 (1A) 183-187;
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Potent Cytotoxic Activity of Saururus cernuus Extract on Human Colon and Breast Carcinoma Cultures under Normoxic Conditions
RAMESH B. BADISA, VEERA L. D. BADISA, EVAN H. WALKER and LEKAN M. LATINWO

Anticancer Research January 2007, 27 (1A) 189-193;
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Antitumor Activity and Pharmacokinetics of Liposomes Containing Lipophilic Gemcitabine Prodrugs
PAOLA BRUSA, MARIA LAURA IMMORDINO, FLAVIO ROCCO and LUIGI CATTEL

Anticancer Research January 2007, 27 (1A) 195-199;
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Macrocyclic Lathyrane Diterpenes as Antitumor Promoters
ROZÁLIA PUSZTAI, MARIA-JOSÉ U. FERREIRA, NOÉLIA DUARTE, HELGA ENGI and JOSEPH MOLNAR

Anticancer Research January 2007, 27 (1A) 201-205;
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The Proteasome Inhibitor Bortezomib Augments Anti-proliferative Effects of Mistletoe Lectin-I and the PPAR-Á Agonist Rosiglitazone in Human Melanoma Cells
CHRISTIAN FREUDLSPERGER, ANKA THIES, UWE PFÜLLER and UDO SCHUMACHER

Anticancer Research January 2007, 27 (1A) 207-213;
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Fas/Fas-ligand Expressions in Primary Breast Cancer are Significant Predictors of its Skeletal Spread
MAREK BĘBENEK, DANUTA DUŚ and JOANNA KOŹLAK

Anticancer Research January 2007, 27 (1A) 215-218;
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Bcl-2 Expression in Breast Cancer: A Comparative Study at the mRNA and Protein Level
FERNANDO MARTÍNEZ-ARRIBAS, TERESA ALVAREZ, GABRIELA DEL VAL, ELENA MARTÍN-GARABATO, MARÍA-JOSÉ NÚÑEZ-VILLAR, RAUL LUCAS, JAIME SÁNCHEZ, ARMANDO TEJERINA and JOSÉ SCHNEIDER

Anticancer Research January 2007, 27 (1A) 219-222;
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Cytotoxic Activity and Absence of Tumor Growth Stimulation of Standardized Mistletoe Extracts in Human Tumor Models In Vitro
GERHARD KELTER, JÖRG M. SCHIERHOLZ, IMMA U. FISCHER and HEINZ-HERBERT FIEBIG

Anticancer Research January 2007, 27 (1A) 223-233;
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CASC2a Gene is Down-regulated in Endometrial Cancer
PAOLA BALDINU, ANTONIO COSSU, ANTONELLA MANCA, MARIA P. SATTA, MARIA C. SINI, GRAZIA PALOMBA, SALVATORE DESSOLE, PIERLUIGI CHERCHI, LAURA MARA, FRANCESCO TANDA and GIUSEPPE PALMIERI

Anticancer Research January 2007, 27 (1A) 235-243;
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Involvement of Tiam1 in Apoptosis Induced by Bufalin in HeLa Cells
HONG CAO, TOSHIKO SHIBAYAMA-IMAZU, YUTAKA MASUDA, TOSHIMASA SHINKI, SHIGEO NAKAJO and KAZUYASU NAKAYA

Anticancer Research January 2007, 27 (1A) 245-249;
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Expression of Type 2 Hexokinase and Mitochondria-related Genes in Gastric Carcinoma Tissues and Cell Lines
MINSUK RHO, JIN KIM, CHANG DO JEE, YOU MIE LEE, HEE EUN LEE, MIN A KIM, HYE SEUNG LEE and WOO HO KIM

Anticancer Research January 2007, 27 (1A) 251-258;
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Maspin Expression was Involved in Colorectal Adenoma-Adenocarcinoma Sequence and Liver Metastasis of Tumors
HUACHUAN ZHENG, KOICHI TSUNEYAMA, CHUNMEI CHENG, HIROYUKI TAKAHASHI, ZHENGGUO CUI, YOSHIHIRO MURAI, KAZHIRO NOMOTO and YASUO TAKANO

Anticancer Research January 2007, 27 (1A) 259-265;
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Regulation of Ovarian Carcinoma SKOV-3 Cell Proliferation and Secretion of MMPs by Autocrine IL-6
ALEX RABINOVICH, LIAT MEDINA, BENJAMIN PIURA, SHRAGA SEGAL and MAHMOUD HULEIHEL

Anticancer Research January 2007, 27 (1A) 267-272;
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Seliciclib (CYC202; r-Roscovitine) in Combination with Cytotoxic Agents in Human Uterine Sarcoma Cell Lines
HELEN M. COLEY, CHRISTINE F. SHOTTON and HILARY THOMAS

Anticancer Research January 2007, 27 (1A) 273-278;
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Prognostic Factors in Hungarian Breast Cancer Patients
EDIT NÁDASI, BÉLA ANGA, JÁNOS SÁNDOR, JUDIT MEGYESI, DEZSO KELEMEN, MARCELLA MOTTOLESE, PIER GIORGIO NATALI, GÉZA HEGEDUS, ISTVÁN ARANY and ISTVÁN EMBER

Anticancer Research January 2007, 27 (1A) 279-282;
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Relation between Human Papillomavirus Positivity and p16 Expression in Head and Neck Carcinomas - A Tissue Microarray Study
FRANK KÖNIG, GISBERT KREKELER, JOHANNES F. HÖNIG, CARLOS CORDON-CARDO, GÖSTA FISCHER and MONIKA KORABIOWSKA

Anticancer Research January 2007, 27 (1A) 283-288;
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Ascorbic Acid Induces Apoptosis in Adult T-cell Leukemia
STEVE HARAKEH, MONA DIAB-ASSAF, JIHANE C. KHALIFE, KHALIL A. ABU-EL-ARDAT, ELIAS BAYDOUN, ALEKSANDRA NIEDZWIECKI, MARWAN E. EL-SABBAN and MATHIAS RATH

Anticancer Research January 2007, 27 (1A) 289-298;
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Antitumor Efficacy of the Cytotoxic RNase, Ranpirnase, on A549 Human Lung Cancer Xenografts of Nude Mice
INTAE LEE, ANNA KALOTA, ALAN M. GEWIRTZ and KUSLIMA SHOGEN

Anticancer Research January 2007, 27 (1A) 299-307;
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In Vitro Gene Transfer Using Cationic Vectors, Electroporation and their Combination
WANLOP WEECHARANGSAN, PRANEET OPANASOPIT and ROBERT J. LEE

Anticancer Research January 2007, 27 (1A) 309-313;
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Inhibition of Angiogenesis via FGF-2 Blockage in Primitive and Bone Metastatic Renal Cell Carcinoma
ELISABETTA CENNI, FRANCESCA PERUT, DONATELLA GRANCHI, SOFIA AVNET, ILARIA AMATO, MARIA LUISA BRANDI, ARMANDO GIUNTI and NICOLA BALDINI

Anticancer Research January 2007, 27 (1A) 315-319;
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In Vitro Histoculture Drug Response Assay and In Vivo Blood Chemistry of a Novel Pt(IV) Compound, K104
YOUNG-EE KWON, JUNG-YOUL PARK and WON-KYU KIM

Anticancer Research January 2007, 27 (1A) 321-326;
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NF-κB-independent Induction of Endothelial Cell Apoptosis by the Vascular Disrupting Agent DMXAA
SEE-TARN WOON, SANDY S.-C. HUNG, DEREK C.F. WU, MARY ANN SCHOOLTINK, RACHEL SUTHERLAND, BRUCE C. BAGULEY, QI CHEN, LAWRENCE W. CHAMLEY and LAI-MING CHING

Anticancer Research January 2007, 27 (1A) 327-334;
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Prognostic Significance of Metallothionein, p53 Protein and Ki-67 Antigen Expression in Laryngeal Cancer
WOJCIECH PASTUSZEWSKI, PIOTR DZIEGIEL, TOMASZ KRECICKI, MARZENA PODHORSKA-OKOLOW, URSZULA CIESIELSKA, ELZBIETA GORZYNSKA and MACIEJ ZABEL

Anticancer Research January 2007, 27 (1A) 335-342;
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(2E)-N,N-dibutyl-3-(4-hydroxy-3-methoxyphenyl)acrylamide Induces Apoptosis and Cell Cycle Arrest in HL-60 Cells
CHUN-JEN CHEN, MEI-HUA HSU, SHENG-CHU KUO, YA-YUN LAI, JING-GUNG CHUNG and LI-JIAU HUANG

Anticancer Research January 2007, 27 (1A) 343-349;
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Modulatory Effects of Heparin on Cellular Accumulation and Cytotoxicity of Doxorubicin in MRP1-overexpressing HL60/doxo Cells
ANTONIO ANGELINI, GIULIANO CIOFANI, GIOVANNA BACCANTE, CONCETTA DI FEBBO, CARMINE DI ILIO, FRANCO CUCCURULLO and ETTORE PORRECA

Anticancer Research January 2007, 27 (1A) 351-355;
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Inhibition of Breast Cancer Cell Proliferation by Style Constituents of Different Crocus Species
DIMITRA G. CHRYSSANTHI, FOTINI N. LAMARI, GREGORIS IATROU, ADAMANTIA PYLARA, NIKOS K. KARAMANOS and PAUL CORDOPATIS

Anticancer Research January 2007, 27 (1A) 357-362;
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Comparative Cytotoxicity and ROS Generation by Curcumin and Tetrahydrocurcumin Following Visible-light Irradiation or Treatment with Horseradish Peroxidase
TOSHIKO ATSUMI, KEIICHI TONOSAKI and SEIICHIRO FUJISAWA

Anticancer Research January 2007, 27 (1A) 363-371;
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A Role for DHX32 in Regulating T-cell Apoptosis
ZAMAN ALLI, YONG CHEN, SARAH ABDUL WAJID, BANDAR AL-SAUD and MOHAMED ABDELHALEEM

Anticancer Research January 2007, 27 (1A) 373-377;
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The Role of Ca⁺² on Rhein-induced Apoptosis in Human Cervical Cancer Ca Ski Cells
SIU-WAN IP, YUEH-SHAN WENG, SHUW-YUAN LIN, MEI-DUE YANG, NOU-YING TANG, CHIN-CHENG SU and JING-GUNG CHUNG

Anticancer Research January 2007, 27 (1A) 379-389;
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Mast Cell and Eosinophil Interaction in Gastric Carcinomas: Ultrastructural Observations
R.A. CARUSO, F. FEDELE, V. ZUCCALÀ, M.G. FRACASSI and A. VENUTI

Anticancer Research January 2007, 27 (1A) 391-394;
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Morin Inhibits the Growth of Human Leukemia HL-60 Cells via Cell Cycle Arrest and Induction of Apoptosis through Mitochondria Dependent Pathway
HSIU-MAAN KUO, LI-SHENG CHANG, YA-LING LIN, HSU-FENG LU, JAI-SING YANG, JAU-HONG LEE and JING-GUNG CHUNG

Anticancer Research January 2007, 27 (1A) 395-405;
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Primary Cultured Human Breast Epithelial Cells Up-regulate Protein Disulfide Isomerase in Response to Zeranol
MICHAEL SCOTT UPDIKE, JOSEPH C. SAWDY, LI-SHU WANG, SULING LIU, YI-WEN HUANG, WEIPING YE, WILLIAM B. FARRAR, YOUNG C. LIN and MACDONALD WICK

Anticancer Research January 2007, 27 (1A) 407-410;
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Telomere Length and Telomerase Activity in Extra-abdominal Desmoid Tumors
TOSHIHIRO MATSUO, EISO HIYAMA, TAKASHI SUGITA, SHOJI SHIMOSE, TADAHIKO KUBO, YU MOCHIZUKI, NOBUO ADACHI and MITSUO OCHI

Anticancer Research January 2007, 27 (1A) 411-415;
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Pharmacokinetics of Albendazole in New Zealand White Rabbits: Oral versus Intraperitoneal Administration
ZHAO-YAN CAI, PETER GALETTIS, YING LU, DAVID L. MORRIS and MOHAMMAD H. POURGHOLAMI

Anticancer Research January 2007, 27 (1A) 417-422;
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Imatinib Mesylate Inhibits Tumorigenicity of Malignant Fibrous Histiocytoma Cells In Vivo
ISTAN IRSAN, TOSHIHIRO AKISUE, HITOMI HARA, TAKUYA FUJIMOTO, MASAYA IMABORI, MINORU DOITA, RYOSUKE KURODA, HIROYUKI FUJIOKA, TERUYA KAWAMOTO, TETSUJI YAMAMOTO and MASAHIRO KUROSAKA

Anticancer Research January 2007, 27 (1A) 423-429;
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Biodistribution and Radioimmunotherapy of SCCHN in Xenotransplantated SCID Mice with a ¹³¹I-labelled Anti-EpCAM Monoclonal Antibody
MICHAELA ANDRATSCHKE, FRANZ JOSEF GILDEHAUS, VERONIKA JOHANNSON, BAERBEL SCHMITT, BRIGITTE MACK, GILBERT REISBACH, STEPHAN LANG, HORST LINDHOFER, REINHARD ZEIDLER, BARBARA WOLLENBERG and CHRISTIAN W. LUEBBERS

Anticancer Research January 2007, 27 (1A) 431-436;
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Apoptosis in Brain Tumors: Prognostic and Therapeutic Considerations
MARTA MELLAI and DAVIDE SCHIFFER

Anticancer Research January 2007, 27 (1A) 437-448;
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Expression of High Mobility Group Box Chromosomal Protein-1 (HMGB-1) in Gastric Cancer
HIDENORI AKAIKE, KOJI KONO, HIDEMITSU SUGAI, AKIHIRO TAKAHASHI, KOUSAKU MIMURA, YOSHIHIKO KAWAGUCHI and HIDEKI FUJII

Anticancer Research January 2007, 27 (1A) 449-457;
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Association of Matrix Metalloproteinase-1 (-1607 1G/2G) Polymorphism with Increased Risk for Oral Squamous Cell Carcinoma
ELEFTHERIOS VAIRAKTARIS, CHRISTOS YAPIJAKIS, SPYRIDOULA DERKA, ZOE SEREFOGLOU, STAVROS VASSILIOU, EMEKA NKENKE, VASSILIS RAGOS, ANTONIS VYLLIOTIS, SOFIA SPYRIDONIDOU, CHRISTOS TSIGRIS, ATHANASIOS YANNOPOULOS, CHRISTINA TESSEROMATIS, FRIEDRICH W NEUKAM and EFSTRATIOS PATSOURIS

Anticancer Research January 2007, 27 (1A) 459-464;
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Histone Deacetylase Inhibitors, but not Vincristine, Cooperate with Radiotherapy to Induce Cell Death in Medulloblastoma
K. SARAVANA KUMAR, JÜRGEN SONNEMANN, LE THI THU HONG, CORNELIS BUURMAN, FRANK ADLER, MANFRED MAASS, UWE VÖLKER and JAMES F. BECK

Anticancer Research January 2007, 27 (1A) 465-470;
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Pharmacokinetics of Liposomal Cisplatin (Lipoplatin) in Combination with 5-FU in Patients with Advanced Head and Neck Cancer: First Results of a Phase III Study
C.F. JEHN, T. BOULIKAS, A. KOURVETARIS, K. POSSINGER and D. LÜFTNER

Anticancer Research January 2007, 27 (1A) 471-475;
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Similar Patterns of Loss of Heterozygosity in Serum of Adenocarcinoma of the Distal Oesophagus and the Cardia in Early Diagnosis
ROBIN WACHOWIAK, JUSSUF T. KAIFI, PAULUS G. SCHURR, PETRA MERKERT, EMRE YEKEBAS, HEIDI SCHWARZENBACH, TIM STRATE, GUIDO SAUTER and JAKOB R. IZBICKI

Anticancer Research January 2007, 27 (1A) 477-481;

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