Multiorgan Resections for Advanced Colorectal Cancer

Abstract

Background: A retrospective review is presented of a single institution's experience with multivisceral resections for locally-advanced colorectal cancer. Materials and Methods: Twenty-eight patients, who had undergone R0 multiorgan resection, were identified from the database of a total of 1150 patients operated on for colorectal carcinoma in the years 1995-2005 at a single center. There were twelve total pelvic exenterations and 16 patients had undergone en bloc primary tumor resection with adherent organs, such as the spleen, diaphragm, pancreas, stomach, kidney, etc. The patients were followed-up according to a standard protocol. Results: The post-operative mortality was 7%, the average follow-up 21.6 months and the 5-year survival 45%. Conclusion: Our results confirmed that, in the case of invasion of colorectal cancer to the adjacent intra-abdominal organs or structures, multiorgan resection offers the only chance of potentially-curative treatment.