Table of Contents

Experimental Studies

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  Modulating ICBP90 to Suppress Human Ribonucleotide Reductase M2 Induction Restores Sensitivity to Hydroxyurea Cytotoxicity

  FRANK UN, CHRISTINA QI, MEGAN PROSSER, NORBY WANG, BINGSEN ZHOU, CHRISTIAN BRONNER and YUN YEN

  Anticancer Research July 2006, 26 (4B) 2761-2767;
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  Concomitant Cell Growth and Differentiation are Dependent on ErbB1 and Integrin Activation in an Autonomously Surviving Colon Adenocarcinoma: Involvement of Autocrine Amphiregulin Secretion

  VÉRONIQUE PICHARD, YOLANDE BERTHOIS, MONIQUE ROCCABIANCA, CHARLES PRÉVÔT, MARCEL SARRAZIN, HENRI PORTUGAL, SHANT KUMAR, PAT KUMAR and JEAN-BAPTISTE ROGNONI

  Anticancer Research July 2006, 26 (4B) 2769-2783;
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  Comparison of ID8 MOSE and VEGF-modified ID8 Cell Lines in an Immunocompetent Animal Model for Human Ovarian Cancer

  MARGIT MARIA JANÁT-AMSBURY, JAMES WILLIAM YOCKMAN, MATTHEW LINLEY ANDERSON, DIRK GÜNTER KIEBACK and SUNG WAN KIM

  Anticancer Research July 2006, 26 (4B) 2785-2789;
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  Antiproliferative and Proapoptotic Activities of Pyranoxanthenones, Pyranothioxanthenones and their Pyrazole-fused Derivatives in HL-60 Cells

  ELISABETH M. PERCHELLET, MARY M. WARD, ALEXIOS-LEANDROS SKALTSOUNIS, IOANNIS K. KOSTAKIS, NICOLE POULI, PANAGIOTIS MARAKOS and JEAN-PIERRE H. PERCHELLET

  Anticancer Research July 2006, 26 (4B) 2791-2804;
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  Activation of Akt and mTOR in CD34⁺/K15⁺ Keratinocyte Stem Cells and Skin Tumors During Multi-stage Mouse Skin Carcinogenesis

  NESRINE I. AFFARA, CAROL S. TREMPUS, BRANDON L. SCHANBACHER, PING PEI, SUSAN R. MALLERY, JOHN A. BAUER and FREDIKA M. ROBERTSON

  Anticancer Research July 2006, 26 (4B) 2805-2820;
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  Establishment and Characterization of Amylase-producing Lung Adenocarcinoma Cell Line, IMEC-2

  HIROSHI YOKOUCHI, KOICHI YAMAZAKI, HAJIME ASAHINA, MASAHIKO SHIGEMURA, TAKANORI MORIYAMA, KAZUO TAKAOKA, JUN MORIYA, TOMOO ITOH, ICHIRO KINOSHITA, HIROTOSHI DOSAKA-AKITA, YUTAKA TSUTSUMI and MASAHARU NISHIMURA

  Anticancer Research July 2006, 26 (4B) 2821-2827;
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  Reduced Expression Level of Mgmt mRNA and β-Catenin Gene Mutation in Rat Colon Tumors

  TATSUYA KINJO, MASUMI SUZUI, TAKAMITSU MORIOKA, MORIHIKO INAMINE, TATSUYA KANESHIRO, JUNYA ARAKAKI, ITARU CHIBA, NAO SUNAGAWA, TADASHI NISHIMAKI and NAOKI YOSHIMI

  Anticancer Research July 2006, 26 (4B) 2829-2832;
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  Allelic Status of Chromosomes 17p, 18q, 22q, 3p and their Clinical Usefulness in Colorectal Cancer

  SHIN FUJITA, HIDEO BABA, SEIICHIRO YAMAMOTO, TAKAYUKI AKASU, YOSHIHIRO MORIYA and KOKICHI SUGANO

  Anticancer Research July 2006, 26 (4B) 2833-2840;
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  First In Vivo Evaluation of Liposome-encapsulated ²²³Ra as a Potential Alpha-particle-emitting Cancer Therapeutic Agent

  THORA J. JONASDOTTIR, DARRELL R. FISHER, JØRGEN BORREBÆK, ØYVIND S. BRULAND and ROY H. LARSEN

  Anticancer Research July 2006, 26 (4B) 2841-2848;
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  Decrease of Telomeres and Increase of Interstitial Telomeric Sites in Chromosomes of Short-term Cultured Gastric Carcinoma Cells Detected by Fluorescence In Situ Hybridization

  KIYOTAKA KASHIMA, ATSUSHI NANASHIMA, TORU YASUTAKE, TERUMITSU SAWAI, TAKASHI TSUJI, SHIGEKAZU HIDAKA, FUMITAKA AKAMA, KOUSEI MIYASHITA, YUTAKA TAGAWA and TAKESHI NAGAYASU

  Anticancer Research July 2006, 26 (4B) 2849-2855;
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  Prostaglandin E₂ Receptor Subtype 2 (EP₂) Null Mice are Protected Against Murine Lung Tumorigenesis

  ROBERT L. KEITH, MARK W. GERACI, S. PATRICK NANA-SINKAM, RICHARD M. BREYER, TYLER M. HUDISH, AMY M. MEYER, ALVIN M. MALKINSON and LORI D. DWYER-NIELD

  Anticancer Research July 2006, 26 (4B) 2857-2861;
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  The Predominant CD44 Splice Variant in Prostate Cancer Binds Fibronectin, and Calcitonin Stimulates its Expression

  KENNETH A. ICZKOWSKI, A. LEVI OMARA-OPYENE and GIRISH V. SHAH

  Anticancer Research July 2006, 26 (4B) 2863-2872;
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  Germ Line Insertions of Moloney Murine Leukemia Virus in the TLL Mouse Causes Site-specific Differences in Lymphoma/Leukemia Frequency and Tumor Immunophenotype

  ANN-SOFIE JOHANSSON, MARIA ERIKSSON, ULRIKA NORÉN-NYSTRÖM, ÅSA LAREFALK, BJÖRN ERIKSSON and DAN HOLMBERG

  Anticancer Research July 2006, 26 (4B) 2873-2878;
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  Association of the Methylenetetrahydrofolate Reductase Polymorphism in Korean Patients with Childhood Acute Lymphoblastic Leukemia

  NAM KEUN KIM, SO YOUNG CHONG, MOON JU JANG, SEUNG HO HONG, HEUNG SIK KIM, EUN KYUNG CHO, JUNG AE LEE, MYUNG JU AHN, CHUL SOO KIM and DOYEUN OH

  Anticancer Research July 2006, 26 (4B) 2879-2881;
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  Quantitative Structure-cytotoxicity Relationship Analysis of Coumarin and its Derivatives by Semiempirical Molecular Orbital Method

  MARIKO ISHIHARA, YOSHIKO YOKOTE and HIROSHI SAKAGAMI

  Anticancer Research July 2006, 26 (4B) 2883-2886;
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  Experimental Model and Immunohistochemical Analyses of U87 Human Glioblastoma Cell Xenografts in Immunosuppressed Rat Brains

  TADEJ STROJNIK, RAJKO KAVALAR and TAMARA T. LAH

  Anticancer Research July 2006, 26 (4B) 2887-2900;
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  Expression of Smad4 and TGF-β2 in Colorectal Carcinoma

  CH. KOUVIDOU, C. LATOUFIS, E. LIANOU, G. KOUVATSEAS, E. KAKOURI, D. ANAGNOSTAKIS, V. VRETTOU-ARAVANI, E. BETSI and S. KARATAPANIS

  Anticancer Research July 2006, 26 (4B) 2901-2907;
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  C-MYC Locus Amplification as Metastasis Predictor in Intestinal-type Gastric Adenocarcinomas: CGH Study in Brazil

  ROMMEL RODRÍGUEZ BURBANO, PAULO PIMENTEL ASSUMPÇÃO, MARIANA FERREIRA LEAL, DANIELLE QUEIROZ CALCAGNO, ADRIANA COSTA GUIMARÃES, ANDRÉ SALIM KHAYAT, SYLVIA SATOMI TAKENO, ELIZABETH SUCHI CHEN and MARÍLIA DE ARRUDA CARDOSO SMITH

  Anticancer Research July 2006, 26 (4B) 2909-2914;
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  Preventive Effect of Ortho Dimer of Butylated Hydroxyanisole on Activator Protein-1 Activation and Cyclooxygenase-2 Expression in Macrophages Stimulated by Fimbriae of Porphyromonas gingivalis, an Oral Anaerobe

  YUKIO MURAKAMI, MASAO SHOJI, TAKAKO OGIWARA, SHOJI TANAKA, ICHIRO YOKOE and SEIICHIRO FUJISAWA

  Anticancer Research July 2006, 26 (4B) 2915-2920;
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  Inhibition of NO Production in LPS-stimulated Mouse Macrophage-like Cells by Trihaloacetylazulenes

  NOBUHARU OHSHIMA, YOSHIAKI AKATSU, MASAYUKI NISHISHIRO, HIDETSUGU WAKABAYASHI, TERUO KURIHARA, KAZUE SATOH, NOBORU MOTOHASHI, KEN HASHIMOTO and HIROSHI SAKAGAMI

  Anticancer Research July 2006, 26 (4B) 2921-2927;
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  Preliminary Study of Chemosenstivity Tests in Osteosarcoma Using a Histoculture Drug Response Assay

  BY SOO YONG LEE, DAE GEUN JEON, WAN HYUNG CHO, WON SEOK SONG, MOON BO KIM and JONG HOON PARK

  Anticancer Research July 2006, 26 (4B) 2929-2932;
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  Predicting Tumor Cell Repopulation After Response: Mathematical Modeling of Cancer Cell Growth

  MING ZHANG, CHANDRA DAS, HERNAN VASQUEZ, DOLLY AGUILERA, PETER E. ZAGE, VIDYA GOPALAKRISHNAN and JOHANNES E. WOLFF

  Anticancer Research July 2006, 26 (4B) 2933-2936;
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  Histamine and Selenium in Lung Cancer

  FILIPPO DELLA ROVERE, ANGELO GRANATA, DARIO FAMILIARI, AGATA ZIRILLI, FRANCESCO CIMINO and ANTONIO TOMAINO

  Anticancer Research July 2006, 26 (4B) 2937-2942;
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  The RNA Interference of Amino Acid Transporter LAT1 Inhibits the Growth of KB Human Oral Cancer Cells

  CHANG-HYUN KIM, KYUNG JIN PARK, JUNG RIM PARK, YOSHIKATSU KANAI, HITOSHI ENDOU, JOO-CHEOL PARK and DO KYUNG KIM

  Anticancer Research July 2006, 26 (4B) 2943-2948;
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  Expression of Dihydrodiol Dehydrogenase and Resistance to Chemotherapy and Radiotherapy in Adenocarcinoma Cells of Lung

  JUNG-JYH HUNG, KUAN-CHIH CHOW, HAO-WEI WANG and LIANG-SHUN WANG

  Anticancer Research July 2006, 26 (4B) 2949-2955;
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  The Co-expression of c-myc and p53 Increases and Reaches a Plateau Early in Oral Oncogenesis

  VERONICA PAPAKOSTA, ELEFTHERIOS VAIRAKTARIS, ANTONIS VYLLIOTIS, SPYRIDOULA DERKA, EMEKA NKENKE, STAVROS VASSILIOU, ANDREAS LAZARIS, CONSTANTINOS MOUROUZIS, GEORGIOS RALLIS, SOFIA SPYRIDONIDOU, SOFIA ANAGNOSTOPOULOU, DESPINA PERREA, ISMINI DONTA, CHRISTOS YAPIJAKIS and EFSTRATIOS PATSOURIS

  Anticancer Research July 2006, 26 (4B) 2957-2962;
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  Monoclonal Antibody to Human Esophageal Cancer Endothelium Inhibits Angiogenesis and Tumor Growth

  YUSHAN ZHANG, YULIANG RAN, LONG YU, HAI HU, ZHUAN ZHOU, LIXIN SUN, JINNING LOU and ZHIHUA YANG

  Anticancer Research July 2006, 26 (4B) 2963-2970;
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  Comparative Promoter Analysis of Doxorubicin Resistance-associated Genes Suggests E47 as a Key Regulatory Element

  ANDRÁS GYÖRFFY, BARNA VÁSÁRHELYI, DOMINIKA SZÖKE, MANFRED DIETEL, TIVADAR TULASSAY and BALÁZS GYÖRFFY

  Anticancer Research July 2006, 26 (4B) 2971-2976;
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  Inhibition of Caveolin-1 Expression by Incadronate in PC-3 Prostate Cells

  KAZUHIRO IGUCHI, SHINJI MATSUNAGA, TORU NAKANO, SHIGEYUKI USUI and KAZUYUKI HIRANO

  Anticancer Research July 2006, 26 (4B) 2977-2981;
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  Tissue Microarray Analysis of FAS, Bcl-2, Bcl-x, ER, PgR, Hsp60, p53 and Her2-neu in Breast Carcinoma

  VALERIA SEBASTIANI, CLAUDIO BOTTI, UGO DI TONDO, PAOLO VISCA, LAURA PIZZUTI, GIUSEPPE SANTEUSANIO and PIERO LUIGI ALO

  Anticancer Research July 2006, 26 (4B) 2983-2987;
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  The Expression of Hypoxia-inducible Factor-1α (HIF-1α) and Angiogenesis Markers in Hyperplastic and Malignant Prostate Tissue

  ALEXANDROS LEKAS, ANDREAS C. LAZARIS, CHARALAMPOS DELIVELIOTIS, MICHAIL CHRISOFOS, CHRISTINA ZOUBOULI, DIMITRIOS LAPAS, THOMAS PAPATHOMAS, IOANNIS FOKITIS and LYDIA NAKOPOULOU

  Anticancer Research July 2006, 26 (4B) 2989-2993;
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  DNA Content Analysis, Expression of Ki-67 and p53 in Rat Urothelial Lesions Induced by N-Butyl-N-(4-Hydroxybutyl) Nitrosamine and Treated with Mitomycin C and Bacillus Calmette-Guérin

  PAULA A. OLIVEIRA, CARLOS PALMEIRA, AURA COLAÇO, LUIS F. DE LA CRUZ P and CARLOS LOPES

  Anticancer Research July 2006, 26 (4B) 2995-3004;
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  Radiation-induced Effect of Adenine (Vitamin B₄) on Mitomycin C Activity. In Vitro Experiments

  JOHANNES HARTMANN and NIKOLA GETOFF

  Anticancer Research July 2006, 26 (4B) 3005-3010;
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  A Comparison of the Tumor Growth Inhibitory Effect of Intermittent and Continuous Administration of the Somatostatin Structural Derivative TT-232 in Various Human Tumor Models

  M. TEJEDA, D. GAÁL, L. HULLÁN, O. CSUKA, R. SCHWAB, O. SZOKOLOCZI and GY. KÉRI

  Anticancer Research July 2006, 26 (4B) 3011-3015;
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  Gemcitabine Treatment of Experimental C6 Glioma: The Effects on Cell Cycle and Apoptotic Rate

  GIULIA CARPINELLI, BARBARA BUCCI, IGEA D'AGNANO, ROSSELLA CANESE, FABRIZIO CAROLI, LAURA RAUS, ERCOLE BRUNETTI, DIANA GIANNARELLI, FRANCA PODO and CARMINE M. CARAPELLA

  Anticancer Research July 2006, 26 (4B) 3017-3024;
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  Ad-FRNK and Ad-p53 Cooperate to Augment Drug-induced Death of a Transformed Cell Line

  LORI KORNBERG

  Anticancer Research July 2006, 26 (4B) 3025-3031;
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  Antiangiogenic Effect of Sulindac Sulfide could be Secondary to Induction of Apoptosis and Cell Cycle Arrest

  S. FLIS, D. SOLTYSIAK-PAWLUCZUK, A. JEDRYCH, Z. JASTRZEBSKI, M. REMISZEWSKA and J. SPLAWINSKI

  Anticancer Research July 2006, 26 (4B) 3033-3041;
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  Antioxidants Modify the Effect of X Rays on Blood Vessels

  CHRISTOS POLYTARCHOU, DIMITRIOS KARDAMAKIS, PANAGIOTIS KATSORIS and EVANGELIA PAPADIMITRIOU

  Anticancer Research July 2006, 26 (4B) 3043-3047;
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  Antiproliferative Effects of Mistletoe (Viscum album L.) Extract in Urinary Bladder Carcinoma Cell Lines

  KONRAD URECH, ARNDT BUESSING, GEORGE THALMANN, HEINRICH SCHAEFERMEYER and PETER HEUSSER

  Anticancer Research July 2006, 26 (4B) 3049-3055;
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  An In Vivo Analysis of the Herbal Compound Essiac®

  BLAIR J.N. LEONARD, DEBORAH A. KENNEDY, FONG-CHI CHENG, KENG-KUANG CHANG, DUGALD SEELY and EDWARD MILLS

  Anticancer Research July 2006, 26 (4B) 3057-3063;
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  Primitive and Bone Metastatic Renal Carcinoma Cells Promote Osteoclastogenesis through Endothelial Cells

  ELISABETTA CENNI, FRANCESCA PERUT, DONATELLA GRANCHI, ILARIA AMATO, SOFIA AVNET, MARIA LUISA BRANDI, ARMANDO GIUNTI and NICOLA BALDINI

  Anticancer Research July 2006, 26 (4B) 3065-3069;
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  Anticancer Versus Antigrowth Activities of Three Analogs of the Growth-inhibitory Peptide: Relevance to Physicochemical Properties

  G. J. MIZEJEWSKI, L. EISELE and R. MACCOLL

  Anticancer Research July 2006, 26 (4B) 3071-3076;