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Research ArticleExperimental Studies

Establishment of a Mouse Gastrointestinal Stromal Tumour Model and Evaluation of Response to Imatinib by Small Animal Positron Emission Tomography

HANS PRENEN, CHRISTOPHE DEROOSE, PETER VERMAELEN, RAF SCIOT, MARIA DEBIEC-RYCHTER, SIGRID STROOBANTS, LUC MORTELMANS, PATRICK SCHÖFFSKI and ALLAN VAN OOSTEROM
Anticancer Research March 2006, 26 (2A) 1247-1252;
HANS PRENEN
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  • For correspondence: hans.prenen{at}uz.kuleuven.ac.be
CHRISTOPHE DEROOSE
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PETER VERMAELEN
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RAF SCIOT
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MARIA DEBIEC-RYCHTER
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SIGRID STROOBANTS
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LUC MORTELMANS
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PATRICK SCHÖFFSKI
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ALLAN VAN OOSTEROM
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Article Information

vol. 26 no. 2A 1247-1252
PMID 
16619531

Published By 
International Institute of Anticancer Research
Print ISSN 
0250-7005
Online ISSN 
1791-7530
History 
  • Received December 22, 2005
  • Accepted February 6, 2006
  • Published online March 1, 2006.

Copyright & Usage 
Copyright© 2006 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved

Author Information

  1. HANS PRENEN1,
  2. CHRISTOPHE DEROOSE2,
  3. PETER VERMAELEN2,
  4. RAF SCIOT3,
  5. MARIA DEBIEC-RYCHTER4,
  6. SIGRID STROOBANTS2,
  7. LUC MORTELMANS2,
  8. PATRICK SCHÖFFSKI1 and
  9. ALLAN VAN OOSTEROM1
  1. 1Laboratory for Experimental Oncology (LEO), Department of General Medical Oncology, Catholic University Leuven, B-3000 Leuven, Belgium
  2. 2Department of Nuclear Medicine, Catholic University Leuven, B-3000 Leuven, Belgium
  3. 3Department of Pathology, Catholic University Leuven, B-3000 Leuven, Belgium
  4. 4Department of Center for Human Genetics, Catholic University Leuven, B-3000 Leuven, Belgium
  1. Correspondence to: Hans Prenen, MD, Laboratory for Experimental Oncology, Department of General Medical Oncology, University Hospital Gasthuisberg, Herestraat 49, B-3000 Leuven, Belgium. Tel: 00 32 (0)16.34.62.85, Fax: 00 32 (0)16.34.69.01, e-mail: hans.prenen{at}uz.kuleuven.ac.be

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Anticancer Research
Vol. 26, Issue 2A
March-April 2006
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Establishment of a Mouse Gastrointestinal Stromal Tumour Model and Evaluation of Response to Imatinib by Small Animal Positron Emission Tomography
HANS PRENEN, CHRISTOPHE DEROOSE, PETER VERMAELEN, RAF SCIOT, MARIA DEBIEC-RYCHTER, SIGRID STROOBANTS, LUC MORTELMANS, PATRICK SCHÖFFSKI, ALLAN VAN OOSTEROM
Anticancer Research Mar 2006, 26 (2A) 1247-1252;

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Establishment of a Mouse Gastrointestinal Stromal Tumour Model and Evaluation of Response to Imatinib by Small Animal Positron Emission Tomography
HANS PRENEN, CHRISTOPHE DEROOSE, PETER VERMAELEN, RAF SCIOT, MARIA DEBIEC-RYCHTER, SIGRID STROOBANTS, LUC MORTELMANS, PATRICK SCHÖFFSKI, ALLAN VAN OOSTEROM
Anticancer Research Mar 2006, 26 (2A) 1247-1252;
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  • A Potent Combination of the Novel PI3K Inhibitor, GDC-0941, with Imatinib in Gastrointestinal Stromal Tumor Xenografts: Long-Lasting Responses after Treatment Withdrawal
  • Establishment and Characterization of a Novel Xenograft Model of Human Gastrointestinal Stromal Tumor in Mice
  • Preclinical and Clinical Evidence that Deoxy-2-[18F]fluoro-D-glucose Positron Emission Tomography with Computed Tomography Is a Reliable Tool for the Detection of Early Molecular Responses to Erlotinib in Head and Neck Cancer
  • Establishment and Characterization of a Human Gastrointestinal Stromal Tumour (GIST) Xenograft in Athymic Nude Mice
  • Inhibitors of Deacetylases Suppress Oncogenic KIT Signaling, Acetylate HSP90, and Induce Apoptosis in Gastrointestinal Stromal Tumors
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