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Research ArticleClinical Studies

Topical Budesonide for Treating Giant Rectal Pseudopolyposis

CHARALAMPOS PILICHOS, ATHENA PREZA, MARIA DEMONAKOU, DIMITRIOS KAPATSORIS and CONSTANTINOS BOURAS
Anticancer Research July 2005, 25 (4) 2961-2964;
CHARALAMPOS PILICHOS
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  • For correspondence: hpilichos@hotmail.com
ATHENA PREZA
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MARIA DEMONAKOU
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DIMITRIOS KAPATSORIS
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CONSTANTINOS BOURAS
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Abstract

Pseudopolyps are a frequent finding in the course of inflammatory bowel disease. They are non-neoplastic lesions resulting from a regenerative and healing process that leaves inflamed colonic mucosa in polypoid configuration. Data about their management is lacking. “Giant” pseudopolyps can be mistaken for adenocarcinomas and, as they rarely regress with medical management alone, a surgical resection is often required. A case of giant pseudopolyposis treated non-surgically, in a patient with concomitant ulcerative colitis and chronic hepatitis B, is reported, representing a co-morbidity complicating an eventual conservative treatment. The clinical implementation of topical budesonide was originally tested, resulting in clinical, endoscopic and histological remission. Budesonide seems a promising therapy for IBD, particularly when a comorbidity with viral hepatitis exist.

  • Inflammatory polyps
  • pseudopolyps
  • ulcerative colitis
  • hepatitis
  • budesonide

Footnotes

  • Received January 10, 2005.
  • Received May 24, 2005.
  • Accepted May 26, 2005.
  • Copyright© 2005 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved
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Anticancer Research: 25 (4)
Anticancer Research
Vol. 25, Issue 4
1 Jul 2005
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Topical Budesonide for Treating Giant Rectal Pseudopolyposis
CHARALAMPOS PILICHOS, ATHENA PREZA, MARIA DEMONAKOU, DIMITRIOS KAPATSORIS, CONSTANTINOS BOURAS
Anticancer Research Jul 2005, 25 (4) 2961-2964;

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Topical Budesonide for Treating Giant Rectal Pseudopolyposis
CHARALAMPOS PILICHOS, ATHENA PREZA, MARIA DEMONAKOU, DIMITRIOS KAPATSORIS, CONSTANTINOS BOURAS
Anticancer Research Jul 2005, 25 (4) 2961-2964;
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