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Review Article

Utilization of Macrophages in Anticancer Therapy: The Macrophage Network Theory

CHIE KOHCHI, HIROYUKI INAGAWA, MAMI HINO, MUTSUMI ODA, KAZUE NAKATA, AYA YOSHIDA, HITOSHI HORI, HIROSHI TERADA, KIMIKO MAKINO, KUNIO TAKIGUCHI and GEN-ICHIRO SOMA
Anticancer Research September 2004, 24 (5C) 3311-3320;
CHIE KOHCHI
1Institute for Health Science, Tokushima Bunri University, Nishihama, Yamashiro-cho, Tokushima-shi, 770-8514
2Institute for Drug Delivery Systems, Tokyo University of Science, Yamazaki, Noda-shi, 278-8510
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HIROYUKI INAGAWA
1Institute for Health Science, Tokushima Bunri University, Nishihama, Yamashiro-cho, Tokushima-shi, 770-8514
2Institute for Drug Delivery Systems, Tokyo University of Science, Yamazaki, Noda-shi, 278-8510
3Faculty of Applied Aqua Biology, National Fisheries University, Nagatahon-machi, Shimonoseki-shi, 759-6595
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MAMI HINO
1Institute for Health Science, Tokushima Bunri University, Nishihama, Yamashiro-cho, Tokushima-shi, 770-8514
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MUTSUMI ODA
1Institute for Health Science, Tokushima Bunri University, Nishihama, Yamashiro-cho, Tokushima-shi, 770-8514
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KAZUE NAKATA
1Institute for Health Science, Tokushima Bunri University, Nishihama, Yamashiro-cho, Tokushima-shi, 770-8514
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AYA YOSHIDA
4Faculty of Engineering, The University of Tokushima, Minamijyousanjima-cho, Tokushima-shi, 770-8506
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HITOSHI HORI
4Faculty of Engineering, The University of Tokushima, Minamijyousanjima-cho, Tokushima-shi, 770-8506
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HIROSHI TERADA
2Institute for Drug Delivery Systems, Tokyo University of Science, Yamazaki, Noda-shi, 278-8510
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KIMIKO MAKINO
2Institute for Drug Delivery Systems, Tokyo University of Science, Yamazaki, Noda-shi, 278-8510
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KUNIO TAKIGUCHI
5Faculty of Medicine, Nagoya City University, Mizuho-cho, Mizuho-ku, Nagoya-shi, 467-8601, Japan
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GEN-ICHIRO SOMA
1Institute for Health Science, Tokushima Bunri University, Nishihama, Yamashiro-cho, Tokushima-shi, 770-8514
2Institute for Drug Delivery Systems, Tokyo University of Science, Yamazaki, Noda-shi, 278-8510
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Abstract

Appropriate and rational modulation of innate immunity may enhance the therapeutic efficacy of emerging immune therapies for treating cancer. One of the crucial cells of innate immunity is the macrophage. The purpose of this article was to review those issues that suggest ways of exploiting macrophage local functions in immune therapy, and to discuss the suitability of low molecular-weight lipopolysaccharides as potent modulators of macrophage functions for immune therapy of cancer.

  • Received June 30, 2004.
  • Accepted July 27, 2004.
  • Copyright© 2004 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved
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Anticancer Research
Vol. 24, Issue 5C
September-October 2004
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Utilization of Macrophages in Anticancer Therapy: The Macrophage Network Theory
CHIE KOHCHI, HIROYUKI INAGAWA, MAMI HINO, MUTSUMI ODA, KAZUE NAKATA, AYA YOSHIDA, HITOSHI HORI, HIROSHI TERADA, KIMIKO MAKINO, KUNIO TAKIGUCHI, GEN-ICHIRO SOMA
Anticancer Research Sep 2004, 24 (5C) 3311-3320;

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Utilization of Macrophages in Anticancer Therapy: The Macrophage Network Theory
CHIE KOHCHI, HIROYUKI INAGAWA, MAMI HINO, MUTSUMI ODA, KAZUE NAKATA, AYA YOSHIDA, HITOSHI HORI, HIROSHI TERADA, KIMIKO MAKINO, KUNIO TAKIGUCHI, GEN-ICHIRO SOMA
Anticancer Research Sep 2004, 24 (5C) 3311-3320;
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