Anticancer Research: 24 (1)

January-February 2004; Volume 24,Issue 1

Experimental Studies

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Effects of Tumor Suppressor Gene (p53) on Brain Tumor Angiogenesis and Expression of Angiogenic Modulators
VICTOR TSE, YUN YUNG, JUSTIN G. SANTARELLI, DAVID JUAN, MICHAEL HSIAO, MARTIN HAAS, GRIFFITH HARSH and GERALD SILVERBERG

Anticancer Research January 2004, 24 (1) 1-10;
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Activated Akt Expression has Significant Correlation with EGFR and TGF-α Expressions in Stage I NSCLC
TORU MUKOHARA, SHINZOH KUDOH, KUNIOMI MATSUURA, SETSUKO YAMAUCHI, TATSUO KIMURA, NARUO YOSHIMURA, HIROSHI KANAZAWA, KAZUTO HIRATA, KIYOTOSHI INOUE, HIDEKI WANIBUCHI, SHOJI FUKUSHIMA and JUNICHI YOSHIKAWA

Anticancer Research January 2004, 24 (1) 11-18;
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CGH Analysis Shows Genetic Similarities and Differences in Atypical Fibroxanthoma and Undifferentiated High Grade Pleomorphic Sarcoma
DANIELA MIHIC-PROBST, JIANMING ZHAO, PARVIN SAREMASLANI, ANGELA BAER, CHRISTIAN OEHLSCHLEGEL, BRUNO AREDES, PAUL KOMMINOTH and PHILIPP U. HEITZ

Anticancer Research January 2004, 24 (1) 19-26;
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Paclitaxel-induced Apoptosis May Occur without a Prior G₂/M-Phase Arrest
JENNIFER M. DZIADYK, MEIHUA SUI, XUEMING ZHU and WEIMIN FAN

Anticancer Research January 2004, 24 (1) 27-36;
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Immune Cell Infiltration of Intrinsic and Metastatic Intracranial Tumours
HERWIG M. STRIK, MANUEL STOLL and RICHARD MEYERMANN

Anticancer Research January 2004, 24 (1) 37-42;
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In-silico Analysis of Kallikrein Gene Expression in Pancreatic and Colon Cancers
GEORGE M. YOUSEF, CARLA A. BORGONO, CYNTHIA POPALIS, GEORGE M. YACOUB, MARY-ELLEN POLYMERIS, ANTONINUS SOOSAIPILLAI and ELEFTHERIOS P. DIAMANDIS

Anticancer Research January 2004, 24 (1) 43-52;
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Spontaneous Apoptosis in the Intra-Ductal Component's Stroma of Breast Invasive Carcinoma
CAROLINE ROULEAU-DUBOIS, MARGUERITE CUNY, GAELLE FERRIERES, JOELLE SIMONY-LAFONTAINE, PHILIPPE ROUANET, JEAN GRENIER, PHILIPPE JEANTEUR, PIERRE BALDET and CHANTAL ESCOT

Anticancer Research January 2004, 24 (1) 53-58;
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Activity of Irofulven against Human Pancreatic Carcinoma Cell Lines In Vitro and In Vivo
EMILY S. VAN LAAR, STEPHANIE ROTH, STEVEN WEITMAN, JOHN R. MACDONALD and STEPHEN J. WATERS

Anticancer Research January 2004, 24 (1) 59-66;
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BZLF1 Controlled by Family Repeat Domain Induces Lytic Cytotoxicity in Epstein-Barr Virus-positive Tumor Cells
HAI WANG, YAN ZHAO, LIANG ZENG, MIN TANG, AMANY EL-DEEB, JIAN JIAN LI and YA CAO

Anticancer Research January 2004, 24 (1) 67-74;
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Activation of Expression of p15, p73 and E-Cadherin in Leukemic Cells by Different Concentrations of 5-Aza-2’-Deoxycytidine (Decitabine)
NUNO J. FARINHA, SEPIDEH SHAKER, MARYSE LEMAIRE, LOUISE MOMPARLER, MARK BERNSTEIN and RICHARD L. MOMPARLER

Anticancer Research January 2004, 24 (1) 75-78;
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Expression of Interleukin-21 and -23 in Human Esophageal Tumors Produced Antitumor Effects in Nude Mice
BAOEN SHAN, LING YU, OSAMU SHIMOZATO, QIAOXIA LI and MASATOSHI TAGAWA

Anticancer Research January 2004, 24 (1) 79-82;
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PCR and Flow Cytometric Analysis of Paclitaxel-inhibited Arylamine N-Acetyltransferase Activity and Gene Expression in Human Osteogenic Sarcoma Cells (U-2 OS)
KO-HSIU LU, DER-YEAN WANG, KO-HUANG LUE, YIE-MING HSIAO, MING-CHIH CHOU, YI-SHUAN CHEN and JING-GUNG CHUNG

Anticancer Research January 2004, 24 (1) 83-90;
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The Inhibitory Effects of Gossypol on Human Prostate Cancer Cells-PC3 are Associated with Transforming Growth Factor Beta₁ (TGFβ₁) Signal Transduction Pathway
JIAHUA JIANG, YASURO SUGIMOTO, SULING LIU, HSIANG-LIN CHANG, KAH-YOUNG PARK, SAMUEL K. KULP and YOUNG C. LIN

Anticancer Research January 2004, 24 (1) 91-100;
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Thorium and Actinium Polyphosphonate Compounds as Bone-seeking Alpha Particle-emitting Agents
GJERMUND HENRIKSEN, ØYVIND S. RULAND and ROY H. LARSEN

Anticancer Research January 2004, 24 (1) 101-106;
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Transitional Increase in Growth Fraction Estimated by Ki-67 Index After Irradiation to Human Tumor in Xenograft
TAKEO TAKAHASHI, TAKASHI NAKANO, KUNIYUKI OKA and KOICHI ANDO

Anticancer Research January 2004, 24 (1) 107-110;
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Numerical Aberrations of Chromosome 17 and the p53 Locus in Small Hepatocellular Carcinomas
HIROSHI YANO, ATSUSHI NANASHIMA, SHIGEKAZU HIDAKA, MASATOSHI HASEBA, KENJI TANAKA, HIROYUKI YAMAGUCHI, TOHRU NAKAGOE, YUTAKA TAGAWA and TAKESHI NAGAYASU

Anticancer Research January 2004, 24 (1) 111-116;
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Repair of Short Oligodeoxyribonucleotides Containing a Stable Adduct and an Apurinic Site by Extracts of MCF-10A1 Cells
KIMBERLY A. CHAPMAN, ERCOLE L. CAVALIERI and ELEANOR G. ROGAN

Anticancer Research January 2004, 24 (1) 117-122;
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A P-glycoprotein- and MRP1-independent Doxorubicin-resistant Variant of the MCF-7 Breast Cancer Cell Line with Defects in Caspase-6, -7, -8, -9 and -10 Activation Pathways
SOO-JUNG PARK, CHING-HAUNG WU and AHMAD R. SAFA

Anticancer Research January 2004, 24 (1) 123-132;
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Modulation of the Constitutive Activated STAT3 Transcription Factor in Pancreatic Cancer Prevention: Effects of Indole-3-Carbinol (I3C) and Genistein
JIAN P. LIAN, BEVERLY WORD, SKEETORA TAYLOR, GEORGE J. HAMMONS and BEVERLY D. LYN-COOK

Anticancer Research January 2004, 24 (1) 133-138;
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β-Galactosidase and α-Mannosidase Inhibit Formation of Multicellular Nodules in Breast Cancer Cell Cultures
KATHLEEN F. ARCARO, JOANN WANG, CHRISTOPHER N. OTIS and BERT M. ZUCKERMAN

Anticancer Research January 2004, 24 (1) 139-144;
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Drug-induced Caspase-3 Activation in a Ewing Tumor Cell Line and Primary Ewing Tumor Cells
CHRISTINE MAUZ-KÖRHOLZ, MARTIN KACHEL, BRITT HARMS-SCHIRRA, ANNE KLEIN-VEHNE, PETER-ULRICH TUNN and DIETER KÖRHOLZ

Anticancer Research January 2004, 24 (1) 145-150;
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Genomic Imbalance and Onco-protein Expression of Ovarian Endometrioid Adenocarcinoma Arisen in an Endometriotic Cyst
F. NOACK, H. SCHMIDT, O. BUCHWEITZ, E. MALIK and H.-P. HORNY

Anticancer Research January 2004, 24 (1) 151-154;
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Numerical Aberrations of Chromosome 8 in Gastric Cancer Detected by Fluorescence In Situ Hybridization
ANNA D. PANANI, ANGELIKI D. FERTI, ALEXANDROS VGERINOS and SATIRIOS A. RAPTIS

Anticancer Research January 2004, 24 (1) 155-160;
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Synthesis and Evaluation of a Hematoporphyrin Derivative in a Folate Receptor-targeted Solid-Lipid Nanoparticle Formulation
PHILLIP J. STEVENS, MASARU SEKIDO and ROBERT J. LEE

Anticancer Research January 2004, 24 (1) 161-166;
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HIF Transcription Factor Expression and Induction of Hypoxic Response Genes in a Retroperitoneal Angiosarcoma
W. KIMRYN RATHMELL, GEZA ACS, M. CELESTE SIMON and DAVID J. VAUGHN

Anticancer Research January 2004, 24 (1) 167-170;
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IFN-Á Responses in Peptide-treated Melanoma Patients Measured by an ELISPOT Assay Using Allogeneic Dendritic Cells
SUSANNE GABRIELSSON, VINCENT BRICHARD, OLIVIER DHELLIN, THIERRY DORVAL and CHRISTIAN BONNEROT

Anticancer Research January 2004, 24 (1) 171-178;
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Abilities of 3,4-Diarylfuran-2-one Analogs of Combretastatin A-4 to Inhibit Both Proliferation of Tumor Cell Lines and Growth of Relevant Tumors in Nude Mice
LICHUN SUN, NATALYA I. VASILEVICH, JOSEPH A. FUSELIER and DAVID H. COY

Anticancer Research January 2004, 24 (1) 179-186;
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Computational Simulation of Chronic Persistent Virus Infection: Factors Determining Differences in Clinical Outcome of HHV-6, HIV-1 and HTLV-1 Infections Including Aplastic, Hyperplastic and Neoplastic Responses
G.R.F. KRUEGER, M.E. BRANDT, G. WANG and L.M. BUJA

Anticancer Research January 2004, 24 (1) 187-198;
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The Matrix Metalloproteinase-21 Gene 572C/T Polymorphism and the Risk of Breast Cancer
ELENA I. SHAGISULTANOVA, INNA A. NOVIKOVA, YURI S. SIDORENKO, GEORGE N. MARCHENKO, ALEX Y. STRONGIN and SERGEI R. MALKHOSYAN

Anticancer Research January 2004, 24 (1) 199-202;
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Potential Antitumor Agents. 34.(1) Synthesis and Antitumor Activity of Guanylhydrazones from Imidazo[2,1-b]thiazoles and from Diimidazo[1,2-a:1,2-c]pyrimidine
ALDO ANDREANI, MASSIMILIANO GRANAIOLA, ALBERTO LEONI, ALESSANDRA LOCATELLI, RITA MORIGI, MIRELLA RAMBALDI, GIANLUCA GIORGI and VIDA GARALIENE

Anticancer Research January 2004, 24 (1) 203-212;
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Simultaneous Targeting of VEGF Message and VEGF Receptor Signaling as a Therapeutic Anticancer Approach
WENYIN SHI and DIETMAR W. SIEMANN

Anticancer Research January 2004, 24 (1) 213-218;
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Apoptosis Induced by Oxaliplatin in Human Colon Cancer HCT15 Cell Line
PAOLO MARCHETTI, DOMENICO A.P. GALLA, F. PAOLA RUSSO, ENRICO RICEVUTO, VINCENZO FLATI, GIAMPIERO PORZIO, CORRADO FICORELLA and M. GRAZIA CIFONE

Anticancer Research January 2004, 24 (1) 219-226;
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Effects of the Medicago scutellata Trypsin Inhibitor (MsTI) on Cisplatin-induced Cytotoxicity in Human Breast and Cervical Cancer Cells
ANNALISA LANZA, ALDO TAVA, MADDALENA CATALANO, LAURA RAGONA, ILARIA SINGUAROLI, FRANCESCO SAVERIO ROBUSTELLI DELLA CUNA and GIOACCHINO ROBUSTELLI DELLA CUNA

Anticancer Research January 2004, 24 (1) 227-234;
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YY1 Transcription Factor is Not Responsible for the Negative Regulation of Hamster Muc1 Transcription
AKINORI HISATSUNE, SANG WON HYUN, INSONG JAMES LEE, STEVEN GEORAS and K. CHUL KIM

Anticancer Research January 2004, 24 (1) 235-240;

Clinical Studies

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Increased Plasma Levels of Serine Proteinase Inhibitors in Lung Cancer Patients
INGA ZELVYTE, ANDERS WALLMARK, EEVA PIITULAINEN, ULLA WESTIN and SABINA JANCIAUSKIENE

Anticancer Research January 2004, 24 (1) 241-248;
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Orbital Rhabdomyosarcoma: Relationship Between DNA Ploidy, P53, Bcl-2, MDR-1 and Ki67 (MIB1) Expression and Clinical Behavior
STEFANIA STAIBANO, RENATO FRANCO, FAUSTO TRANFA, ERNESTO MEZZA, LORENZO LO MUZIO, DIEGO STRIANESE, MARIA ELENA ERRICO, PANTALEO BUFO, GERARDO FERRARA, PASQUALE SOMMA, GELSOMINA MANSUETO, GRECO IMMACOLATA, AMEDEO FIORILLO, GIULIO BONAVOLONTÁ and GAETANO DE ROSA

Anticancer Research January 2004, 24 (1) 249-258;
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Polo-like Kinase 1 (PLK1) Expression is Associated with Cell Proliferative Activity and Cdc2 Expression in Malignant Lymphoma of the Thyroid
YASUHIRO ITO, HIROSHI YOSHIDA, FUMIO MATSUZUKA, NARIAKI MATSUURA, YASUSHI NAKAMURA, HIROKAZU NAKAMINE, KENNICHI KAKUDO, KANJI KUMA and AKIRA MIYAUCHI

Anticancer Research January 2004, 24 (1) 259-264;
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Palliative Management of Malignant Rectosigmoidal Obstruction. Colostomy vs. Endoscopic Stenting. A Randomized Prospective Trial
ENRICO FIORI, ANTONIETTA LAMAZZA, ALESSANDRO DE CESARE, MARCO BONONI, PATRIZIA VOLPINO, ALBERTO SCHILLACI, ANTONINO CAVALLARO and VINCENZO CANGEMI

Anticancer Research January 2004, 24 (1) 265-268;
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Palliative Management of Malignant Antro-pyloric Strictures. Gastroenterostomy vs. Endoscopic Stenting. A Randomized Prospective Trial
ENRICO FIORI, ANTONIETTA LAMAZZA, PATRIZIA VOLPINO, ANTONIO BURZA, CLAUDIA PAPARELLI, GIUSEPPE CAVALLARO, ALBERTO SCHILLACI and VINCENZO CANGEMI

Anticancer Research January 2004, 24 (1) 269-272;
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Immunohistochemical Dihydropyrimidine Dehydrogenase Expression is a Good Prognostic Indicator for Patients with Dukes' C Colorectal Cancer
KENTARO OI, MASATO MAKINO, MAI OZAKI, HIROKI TAKEMOTO, NARIYUKI YAMANE, SEIICHI NAKAMURA, MASAHIDE IKEGUCHI and NOBUAKI KAIBARA

Anticancer Research January 2004, 24 (1) 273-280;
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Loss of BRCA2 Correlates with Reduced Long-term Survival of Sporadic Breast Cancer Patients
J.A. HAMPL, M. HAMPL, G. REIß, R. KOCH, H.-D. SAEGER and H.K. SCHACKERT

Anticancer Research January 2004, 24 (1) 281-290;
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Multidrug Resistance Proteins in Primary and Metastatic Soft-tissue Sarcomas: Down-regulation of P-glycoprotein During Metastatic Progression
RUDY KOMDEUR, WILLEMINA M. MOLENAAR, NYNKE ZWART, HARALD J. HOEKSTRA, EVA VAN DEN BERG and WINETTE T.A. VAN DER GRAAF

Anticancer Research January 2004, 24 (1) 291-296;
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Clinical and Immunohistochemical Analysis of Patients with Unknown Primary Tumour. A Search for Prognostic Factors in UPT
AGNeS J. VAN DE WOUW, ROB L.H. JANSEN, ARJAN W. GRIFFIOEN and HARRY F.P. HILLEN

Anticancer Research January 2004, 24 (1) 297-302;
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Impact of Complementary Mistletoe Extract Treatment on Quality of Life in Breast, Ovarian and Non-small Cell Lung Cancer Patients A Prospective Randomized Controlled Clinical Trial
B. K. PIAO, Y. X. WANG, G. R. XIE, U. MANSMANN, H. MATTHES, J. BEUTH and H. S. LIN

Anticancer Research January 2004, 24 (1) 303-310;
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Catestatin-A Novel Neuropeptide in Carcinoid Tumors of the Appendix
RUPERT PROMMEGGER, CHRISTIAN ENSINGER, CHRISTINE ADLASSNIG, SUCHETA VAINGANKAR, SUSHIL K. MAHATA, JOSEF MARKSTEINER and RAIMUND MARGREITER

Anticancer Research January 2004, 24 (1) 311-316;
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Complete Response of Severe Symptomatic Bone Marrow Metastases from Heavily Pretreated Breast Cancer with a 3-Weekly Trastuzumab Schedule. A Clinical Case
ANTONIO ROSSI, GIUSEPPE COLANTUONI, NICOLA CANTORE, LUIGI PANICO, GIOVANNI DE CHIARA, UMBERTO FERBO and CESARE GRIDELLI

Anticancer Research January 2004, 24 (1) 317-320;
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Differential Expressions of BRCA1 and BRCA2 in Infantile Gynecomastia
DOMINIQUE J. BERNARD-GALLON, PIERRE J. DECHELOTTE, LUDOVIC LE CORRE, NASSERA CHALABI, CECILE VISSAC-SABATIER and YVES-JEAN BIGNON

Anticancer Research January 2004, 24 (1) 321-324;
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The Impact of Stromal Cell Contamination on Chemosensitivity Testing of Head and Neck Carcinoma
RALPH DOLLNER, CHRISTOF GRANZOW, BURKHARD M. HELMKE, ALEXANDRA RUESS, ARNO SCHAD and ANDREAS DIETZ

Anticancer Research January 2004, 24 (1) 325-332;
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Immunohistochemical Detection of HER-2/neu, c-Kit (CD117) and Vascular Endothelial Growth Factor (VEGF) Overexpression in Soft Tissue Sarcomas
ANIL POTTI, APAR KISHOR GANTI, HEIDI FOSTER, STACEY KNOX, BRIAN J. HEBERT, KETKI TENDULKAR, KALEY SHOLES, MICHAEL KOCH and STEVEN KARGAS

Anticancer Research January 2004, 24 (1) 333-338;
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Pulmonary Radiofrequency Ablation - An International Study Survey
KARIN STEINKE, PATRICK E. SEWELL, DAMIEN DUPUY, RICCARDO LENCIONI, THOMAS HELMBERGER, STEPHEN T. KEE, AUGUSTINUS L. JACOB, DEREK W. GLENN, JULIE KING and DAVID L. MORRIS

Anticancer Research January 2004, 24 (1) 339-344;
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Paclitaxel and Carboplatin Concurrent with Radiotherapy for Primary Cervical Cancer
F.Y.F.L DE VOS, A.M.E. BOS, J.A. GIETEMA, E. PRAS, A.G.J. VAN DER ZEE, E.G.E. DE VRIES and P.H.B. WILLEMSE

Anticancer Research January 2004, 24 (1) 345-348;
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Radiotherapy in the Treatment of Stage III-IV Hypopharyngeal Carcinoma
INCENZO TOMBOLINI, MARIO SANTARELLI, NICOLA RAFFETTO, VITTORIO DONATO, MAURIZIO VALERIANI, ANTONIO FERRETTI and R. MAURIZI ENRICI

Anticancer Research January 2004, 24 (1) 349-354;
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Phase II Study of Weekly Oxaliplatin and High-dose Infusional 5-Fluorouracil plus Leucovorin in Pretreated Patients with Metastatic Colorectal Cancer
S. CHIARA, M.T. NOBILE, A. GOZZA, P. TAVEGGIA, A. HEOUAINE, I. PASTRONE, P.L. PERCIVALE, R. LIONETTO, O. SANGUINETI and R. ROSSO

Anticancer Research January 2004, 24 (1) 355-360;
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Molecular and Clinicopathological Analysis of Ovarian Carcinomas With and Without Microsatellite Instability
ATHANASSIOS DELLAS, ALEX PUHL, PETER SCHRAML, SABINE E. THOMKE, JOSEF RÜSCHOFF, MICHAEL J. MIHATSCH and HOLGER MOCH

Anticancer Research January 2004, 24 (1) 361-370;
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Assessment of Microvessel Density in Core Needle Biopsy Specimen in Breast Cancer
LISA RYDÉN, POUL BOIESEN and PER-EBBE JÖNSSON

Anticancer Research January 2004, 24 (1) 371-376;
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Yearly Alterations in Prognostic Factors in Gastric Cancer During the Post-operative Period
CHIKARA KUNISAKI, HIROSHI SHIMADA, HIROTOSHI AKIYAMA, MASATO NOMURA, GORO MATSUDA, YUICHI OTSUKA and HIDETAKA ONO

Anticancer Research January 2004, 24 (1) 377-384;
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Palliative Second-line Treatment with Weekly High-dose 5-Fluorouracil as 24-hour Infusion and Folinic Acid (AIO) plus Oxaliplatin after Pre-treatment with the AIO-Regimen in Colorectal Cancer (CRC)
K. LINK, K. HAPPICH, I. SCHIRNER, B. JÜNGERT, V. BRÜCKL, G. MÄNNLEIN, M. BRÜCKL, S. MERKEL, J. GÖHL, W. HOHENBERGER, E.G. HAHN and A. WEIN

Anticancer Research January 2004, 24 (1) 385-392;
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Long-term Effect of Gefitinib (ZD1839) on Squamous Cell Carcinoma of the Lung
TOSHIYUKI KOZUKI, KATSUYUKI KIURA, HIROSHI UEOKA, MASAHIRO TABATA, HIROSHI DATE, SHUJI HAMAÓAKI, AKIHIRO BESSHO and MITSUNE TANIMOTO

Anticancer Research January 2004, 24 (1) 393-396;

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