Abstract
Background/Aim: We aimed to identify the surgical-pathological risk factors separately for pelvic and para-aortic lymph nodes (LN) metastases in endometrial cancer (EC). Patients and Methods: The study cohort consisted of 179 patients with first diagnosis of EC, who were operated in our Institution between 2007 and 2014. Results: Pelvic and para-aortic LN dissection was performed in 115 patients (64.2%). The positive pelvic and para-aortic LN were diagnosed in 11.3% and 16.1% of cases, respectively. Patients with bad differentiated tumors (G3) showed about 5-times more risk to have affected LN. Deep infiltration of myometrium elevated the risk of pelvic LN infiltration 5 times and of para-aortic LN infiltration 14 times. G3, myometrial infiltration >50% and type II endometrial cancer correlated with a worse progression free survival (PFS) and overall survival (OS). Conclusion: Tumor grade and deep myometrial invasion were the only significant predictors of pelvic and para-aortic lymph node metastases.
- Received May 24, 2016.
- Revision received June 16, 2016.
- Accepted June 21, 2016.
- Copyright© 2016 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved