Abstract
The focus of this mini-review is to identify non-toxic compounds isolated from natural sources (plants) that exhibit specific activity against efflux pumps of specific multidrug-resistant (MDR) cancer cell lines, inhibit proliferation of the MDR cancer cell lines and inhibit the activity of overexpressed efflux pumps of the MDR cancer cell line.
- Non-toxic compounds isolated from natural sources (plants)
- multidrug-resistant cancer cell lines
- induction of apoptosis
- inhibition of P-glycoprotein (ABCB1)
- reversal of multidrug resistance
- review
- Received August 29, 2016.
- Revision received September 8, 2016.
- Accepted September 9, 2016.
- Copyright© 2016 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved