No Infectious Hepatic Complications Following Radioembolization with ⁹⁰Y Microspheres in Patients with Biliodigestive Anastomosis

Abstract

Aim: To retrospectively evaluate infectious hepatic complications of transarterial radioembolization (RE) of the liver in patients with pre-existing biliodigestive anastomosis. Patients and Methods: Patients who underwent RE were retrospectively analyzed. All patients had at least a contrast-enhanced magnetic resonance imaging or contrast-enhanced triple-phase computed tomographic scan before and 6-8 weeks after RE. Results: Overall, 143 patients (67 women, 76 men; median age=65±11.2 years) were analyzed. Nine patients had a biliodigestive anastomosis. The complications were as follows: one case of cholecystitis, three of gastroduodenal ulcer with one ulcer perforation, and six of radioembolization-induced liver disease. There were no infectious complications. There were no major or minor complications in the group with previous biliodigestive anastomosis. Conclusion: Pre-existing bilioenteric anastomoses are not a negative predictive factor for the development of infectious hepatic complications after RE. RE with ⁹⁰Y microspheres can be safely performed following careful patient selection.